An ectopic pregnancy occurs when a fertilized egg grows outside of the uterus. As the pregnancy grows, it can cause the tube to burst rupture. A rupture can cause major internal bleeding. This can be a life-threatening emergency that needs immediate surgery. About one half of all women who have an ectopic pregnancy do not have known risk factors.
This material is for information purposes only. As these protocols have evolved, trials have involved single-dose, two-dose, and multidose Methotrexate for treatment in ectopic pregnancy. Obstet Gynecol ;e1— Online forums also can be a place to get support from other women who have had ectopic pregnancies. Apr; 93 4 Sexually active women should be alert to changes in their bodies, especially if they experience symptoms of an ectopic pregnancy. Box 1 lists absolute and relative contraindications to methotrexate therapy Subsequently after two years, she reported with EP of the other side which was treated conservatively with two doses of MTX corresponding to a rate of 1. A single Clip fetish latex regimen was introduced to minimize side effects, to improve patient compliance and to reduce the overall costs. Louis MO : Wolters Kluwer;
Methotrexate for treatment in ectopic pregnancy. Expectant management
Resolution of an ectopic pregnancy may depend on the methotrexate treatment regimen used and ptegnancy initial hCG level. The first step is to assess for the possibility that the gestation is advancing. A ruptured fallopian tube can cause life-threatening internal bleeding. PUL 8 8 Ultrasound surveillance of resolution of an ectopic pregnancy is not routinely indicated because findings do not predict rupture or time to resolution 59 Radiology ;—
Related letter: Considerations for Identifying Ectopic Pregnancy.
- Methotrexate treatment of unruptured ectopic pregnancy is safe and effective and preserves reproductive potential.
- A pelvic exam can help your doctor identify areas of pain, tenderness, or a mass in the fallopian tube or ovary.
- Methotrexate is a type of medicine that stops cells from dividing.
Methotrexate is a type of medicine that stops cells from dividing. You will need to have blood tests to monitor the level of pregnancy hormone in your blood. The methotrexate will stop the Methotrexate for treatment in ectopic pregnancy and the level of pregnancy hormone in your blood should decrease ectopjc 2 to 4 days. Your doctor will likely want you to have a blood test 2 to 3 times a week, for 2 to 3 weeks. This is to tell if the methotrexate worked to stop the pregnancy. If you have nausea, sip clear fluids like ginger ale or soup broth.
Try to drink often and eat small amounts of dry, starchy food like soda crackers every 15 minutes. If you need to take pain medicine e. If you have any questions about medicine, talk to your doctor or pharmacist. To help relax the muscles that cause cramping, you can use a Methotrexate for treatment in ectopic pregnancy water bottle or a heating pad. Taking hot baths can also help.
You must not get pregnant for at least 3 months after having a methotrexate injection. Talk to your doctor or healthcare provider if you have questions about birth control. Wash your hands with soap and Hidden smurf episode after you go to the washroom. This material is for information purposes only. It should not be used in place of pgegnancy advice, instruction, or treatment.
When should you call for help? Current as of: April 18, Home About MyHealth. Include Images Large Print.
May 14, · INTRODUCTION. An ectopic pregnancy is a pregnancy outside of the uterine cavity. The majority of ectopic pregnancies occur in the fallopian tube (96 percent) , but other possible sites include cervical, interstitial (also referred to as cornual; a pregnancy located in the proximal segment of the fallopian tube that is embedded within the muscular wall of the uterus), hysterotomy scar (eg, in. Nov 27, · Ectopic pregnancy occurs when the embryo fails to implant within the uterine cavity. Methotrexate, a folic acid has been widely used to treat ectopic pregnancy. The aim of this study is to determine the efficacy of methotrexate treatment for Cited by: May 16, · However, although medical management using methotrexate is used commonly, there is no solid consensus regarding dose protocol. Currently, there are three methotrexate protocols for the treatment of an ectopic pregnancy, "multi-dose", "single-dose", or "two-dose".
Methotrexate for treatment in ectopic pregnancy. Tubal Ectopic Pregnancy
Information from references 5 through 8. Decreasing hCG values suggest a failing pregnancy and may be used to monitor spontaneous resolution, but this decrease should not be considered diagnostic. Performance of human chorionic gonadotropin curves in women at risk for ectopic pregnancy: exceptions to the rules. Abstract Objectives Ectopic pregnancy occurs when the embryo fails to implant within the uterine cavity. Although oral methotrexate therapy for ectopic pregnancy has been studied, the outcomes data are sparse and indicate that benefits are limited Intrauterine pregnancy. It is preferred over transabdominal ultrasonography because the transvaginal view allows for direct visualization of an ectopic mass, whereas the transabdominal view does not. Outpatient endometrial aspiration: an alternative to methotrexate for pregnancy of unknown location. Reprod Biomed Online ;— The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Jan; 27 1 This information should not be considered as inclusive of all proper treatments or methods of care or as a statement of the standard of care. Careful follow-up and assessment are required for all women presenting with pain in the few days following methotrexate therapy before assuming that the treatment has failed and if there is need for surgical intervention. ACOG does not guarantee, warrant, or endorse the products or services of any firm, organization, or person. Want to use this article elsewhere?
Committee on Practice Bulletins—Gynecology.
Ectopic pregnancy is an important cause of maternal morbidity and occasionally mortality. The main stays of management for ectopic pregnancy were surgery and medical treatment. Medical management with systemic methotrexate administration avoids the inherent morbidity of anesthesia and surgery is cost-effective, and also offers success rates comparable to surgical management, with no loss in future potential fertility. However, although medical management using methotrexate is used commonly, there is no solid consensus regarding dose protocol.